Showing posts with label Nocera. Show all posts
Showing posts with label Nocera. Show all posts

Sunday, October 19, 2014

Ebola, fate, and appropriately assessing risk.


There has been a lot written about Ebola lately, and lots of talk about it, and fear about it, in the halls of the hospital and clinics where I work, and I would guess lots of other places also. I don’t have any expertise in Ebola, and don’t claim to know what should have been done, or what “we” should be doing going forward, but it is clear that there have been mistakes, or at least major miscalculations, made by the WHO and the CDC and other government agencies. Some of this may be the result of cuts in funding over the last many years, some the result of emphasis on bioterrorism rather than the impact of infectious agents that get transmitted the regular way (“Failures of Competence”, Joe Nocera, October 18, 2014) but has been both sobering as well as a vehicle for administration opponents to attack it. Of course, the attacks may be justified, but there is no reason to think a previous administration would have done better.

First, it is critical to point out that the real problem, suffering, and crisis is in West Africa, in Liberia and Sierra Leone, and Guinea. In countries with little infrastructure and few resources and in the cases of the first two, relatively recent histories of devastating civil wars. The concern about Ebola in the US (so far two home-grown cases, both in nurses who cared for the Liberian man in Texas) needs to be seen in that context. Those countries that are severely affected need major resources, both human and financial, and need them fast. An excellent video analysis of the issues was recently done by Laurie Garrett on a webinar called “The Ebola crisis: the best and worst case scenarios from here”. Thankfully, there is some recognition of the need in these countries among those who are seeking to make political hay of this crisis; my own Senator Jerry Moran has joined others, particularly other Republicans, in calling for closing off flights from the affected countries, but proposes to exempt health workers. Of course, this misses the fact that it is easier to screen folks coming from those countries than people who first travel to other countries and then fly to the US.

What does interest me about the whole discussion in this country around Ebola is the degree to which it illustrates two common flaws in the way people think about problems. One, obviously at play in the case of Ebola, is the fear of the new, unfamiliar, and scary, especially when hyped up by the media. Thus, for example, the reluctance of both patients and staff (encouraged by their families) to come to work in our clinic during the period that a patient at our hospital was being ruled out for Ebola (he didn’t end up having it), even though it is in a separate building and the patient was three layers of isolation deep. This fear is stoked by events such as the revelation that the second nurse to come down with Ebola had been allowed to fly from Texas to Ohio and back on a commercial airliner (although it could just as well be cited as evidence that anyone, working in a hospital or not, might be at risk).

The second is that people often find it easier to worry about, to get worked up about, problems that they are at low risk for but that they cannot do anything about, even when they are not doing what they could do to prevent problems for which they are at much greater risk. I have written in the past about a prototypical patient obsessed by breast cancer, a condition for which she was in fact at no increased risk, who was not doing anything about problems she could act on such as uncontrolled hypertension, cigarette smoking, and unprotected sex with multiple partners. Indeed, my point was that if she was worried about those last three, people would expect her to do something about them since she could – she could take blood pressure medication, stop or cut down on her smoking, and use protection when having sex. But those might be hard. Worrying about breast cancer, something that there was nothing she herself could do to prevent (doctors could order mammograms, at too young an age and far too frequently, but she wouldn’t have to do anything) was, in this sense, easier. Both of these logical flaws were highlighted by comments from the chief medical officer of my hospital, early in the isolation of the possible Ebola patient: “If 20,000 people were dying of Ebola there would be riots in the streets. But every year an average of 22,000 Americans die of influenza, and people still don’t get their flu shots”.

This selective concern is a form of determinism, the topic addressed by Konika Banerjee and Paul Bloom in “Does everything happen for a reason?” in the NY Times, October 19, 2014. They discuss the idea of fate, that things happen that were destined to happen, that experiences of adversity which coincidentally lead to positive outcomes (the man hospitalized for injuries as a result of the 2013 Boston Marathon bombings who falls in love with and marries his nurse) are “meant to be”. They note that while this is most common in people who are religious and believe that God determines everything, it is still a very common belief among atheists. It is an attractive idea, but it is a mis-reading of chance. That is, people pay attention when things seem to fortuitously happen, or a coincidence facilitates something you wanted to happen. (E.g., yesterday morning I heard a part of a 1981 song on the oldies station but couldn’t remember its name; amazingly, when I turned the station back on in the evening, it was playing again! Fated? No, just Rick Springfield’s “Jesse’s Girl”.) We forget how often things do not happen, but remember when they do. Banerjee and Bloom write:
Not everyone would go as far as the atheist Richard Dawkins, who has written that the universe exhibits “precisely the properties we should expect if there is, at bottom, no design, no purpose, no evil, and no good, nothing but blind, pitiless indifference.”
Deists, like Thomas Jefferson I heard yesterday (also on the radio, but NPR this time), believed that the world was so ordered that there must be a creator, although they rejected the detailed instructions that many of their contemporaries took from the Bible or other religious texts. However, the random nature of events, as suggested by Dawkins or by Stephen Jay Gould (“Full House: The Spread of Excellence from Plato to Darwin”) accounts for these just as well.

The same issue of the Times contains a more medically related piece, “Why doctors need stories”, by Peter D. Kramer. I like stories, and I use them a lot (see above for a couple); they make things come alive, tie abstract events to actual lives, create examples in the experience of individual people of phenomena that are harder to understand when we look only at populations. But they can be misused; my story about the woman who was more worried about breast cancer than her smoking or high blood pressure is meant to be an example of how people can choose which facts they believe and which they ignore. It doesn’t prove anything, certainly not that most people act this way, or don’t. It does (I hope) get your attention. We have to be careful how stories are used; “I knew someone who had an abnormal Pap smear and she didn’t do anything and it went away”, while consistent with our most current knowledge about the early course of abnormal Pap smears in young women, is not a valid argument for you to not do anything. Stories tell what they tell; the lessons learned and conclusions reached are up to us.

Banerjee and Bloom end their piece:
If there is such a thing as divine justice or karmic retribution, the world we live in is not the place to find it. Instead, the events of human life unfold in a fair and just manner only when individuals and society work hard to make this happen. We should resist our natural urge to think otherwise.

And, no matter what we think about Ebola, we should get our flu shots.


Saturday, January 12, 2013

Mental Illness and Guns: A public health perspective


I have been somewhat reluctant to write about the issues surrounding the mass shootings that have become epidemic in our country. Since the Newtown elementary school massacre it appears as if everyone else has done so, and I didn’t know what, if anything, I could add that would be of value. I still don’t, but I would like to try to emphasize the public health and medical issues here. Everyone talks about getting beyond rhetoric, but mostly we hear rhetoric and have yet to see results.

In his column in the New York Times on December 28, 2012, “Guns and Mental Illness”, Joe Nocera addresses those two aspects of the controversy, which I agree are the key ones. However, while I generally think his points are valid, I disagree with his characterization that gun control is a “liberal” issue while mental health has been the focus of conservatives. For good, or bad, and too often bad, both issues have been neglected by too many for too long. When it comes to death, dramatically in the case of mass killings such as Newtown or Aurora or Columbine, much more commonly in “simple” individual killings, and most commonly in the case of suicide, they are tied together. Nocera starts with mental health, so I’ll start with guns.

I have written about guns several times before (“Mexican Murders and US Guns”, March 24, 2009,
 “The Arizona shootings: When will we ever learn?“, January 9, 2011, “Why we don’t spend enough on public health”, September 22, 2011, and even discussed a New England Journal of Medicine article (Why we don’t spend enough on public health”)[1]  by Dr. David Hemenway of the Harvard School of Public Health and Director of their Injury Control Research Center and Youth Violence Prevention Center (“Public Health and Changing People's Minds, May 15, 2010). Guns are efficient and effective killing machines. This is, after all, the reason that hunters and warriors like them. They can be made more efficient, by being automatic or semi-automatic, and by having magazines that hold many bullets. These are generally considered positives on the war side (and by gangsters), but are often seen as “un-sporting”, so that most states have laws governing their use in hunting. The statistics on gun violence in the US are staggering, and seen from a public health perspective represent a severe and continuing epidemic. Likely the best book on this topic is “Private Guns, Public Health”[2], by Dr. Hemenway. He presents extensive statistics on injury and death resulting from guns, and emphasizes a addressing this problem through efforts to both increase the safety of guns themselves (as we have for cars) and limiting their availability (as we have for cigarettes). This is a harm-reduction approach.

Much of the data cited by Hemenway is sobering, and some is so downright shocking that one might think it difficult to ignore. There are over 30,000 suicides in the US per year, and a high proportion are from guns, because guns are much more effective, and are less likely to allow a second chance; the “success” rate for suicide by gun exceeds 95% while for intentional overdoses it is less than 5%. One of the populations most at risk for suicide is young men; Hemenway notes that the successful suicide rate in this group is several times higher in “low gun control” states (mostly Southern and Mountain) than in “high gun control” states (mostly Northeast and Hawaii). This is not because of less suicidal intent in, say, Massachusetts than Montana, but the easy availability of guns.[3]

But we know about the effectiveness of guns. You can kill someone with a baseball bat, or a knife, or a lead pipe or wrench or candlestick in the Library, but not as efficiently, reliably, effectively, and potentially randomly as you can with a gun. The recent episode of a knife-wielder in China is one example. Adam Lanza wouldn’t have been able to kill many with a candlestick. Innocent children are rarely victims in drive-by knifings. The NRA used to say “guns don’t kill people, people kill people”. Yes, but they do it much better with guns. Now they say that the solution to “bad guys with guns” is “good guys with guns”. This is so ridiculous (can you imagine a bunch of “good guys” blazing away at whoever they thought might be the shooter in the dark in the Aurora, CO, theater?) that NRA bumper stickers are now being amended by new ones saying “Not MY NRA!” in response.

What about mental health? Nocera does an excellent job of summarizing the problem confronting the chronically mentally ill; with a progressive philosophy of “de-institutionalization” mental hospitals were closed with the promise of comprehensive, community-based mental health services being available in the community. But, of course, funding was not forthcoming for those services, nor does it appear that it will ever be adequate. Nocera is correct in saying conservatives have pointed to mental illness (rather than guns) as the cause of such violence, but in addition to not supporting any gun regulation, these same “conservatives” have led the charge in de-funding and under-funding mental health services. The constituency supporting such services, especially for those who cannot afford private care, is not big or effective enough. Apparently these politicians are in favor of supporting (retroactively) mental health care for those who commit mass murder, but not prospectively for the millions in need. One word that is commonly used for such an approach is “hypocrisy”, but this does not shame politicians.

I have written about the “sensitivity” and “specificity” of tests, particularly with regard to screening.  However, the same concept can be used for assessing risk of any condition, such as mental illness and the probability of committing gun violence on a large scale. If “committing mass murder” (as opposed to individual homicide or suicide) is considered the disease, then assessing for mental illness would be pretty sensitive – that is most mass murderers are mentally ill and there are relatively few “false negatives” – people who are mass murderers but not mentally ill. But it is pathetically not specific, for the overwhelming number of mentally ill persons will never be mass murders. They would be “false positives”. But this in no way means that they should not receiving comprehensive and effective mental health services.

So, which is the greater problem? Which should be addressed first? The answer is both, and, more to the point, either would be an improvement. On guns, there need to be bans on assault and automatic weapons and on high-capacity clips and “cop-killer” bullets, and background checks on gun purchasers and closure of the “gun show loophole”. On mental health, there need to be ubiquitous and well-funded mental health treatment programs in all of our communities, with outreach workers and close collaboration with primary care medical providers. Both strategies are critical, both are quite (although, obviously, not completely) effective in other countries.

But I would be happy if we would do one of them. I mostly, however, hear a lot of talk and am fearful that we will, ultimately not do either.




[1] Hemenway D, “Why we don’t spend enough on public health”, NEJM 6May2010;362(10);1657-8.
[2] Hemenway D. “Private Guns, Public Health”. University of Michigan Press. Ann Arbor. 2004.
[3] Full disclosure: Ten years ago, my 24-year old son committed suicide with a gun. As far as I know, he’d never used one before. He left his home in a “high gun control” state and went to a “low gun control state” where he knew no one, acquired the gun, and completed his suicide. A testimony to the impossibility of preventing suicide? A condemnation of the ease with which he obtained the gun? Make of this what you will.

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